The HIVST Innovation Project pilots innovative approaches to increase access to HIV prevention products for adolescent girls and young women and improve HIV self-testing (HIVST) for adolescents and young people across Ethiopia, Kenya, Malawi, Mozambique, Nigeria, Tanzania, Uganda, Zambia, and Zimbabwe. In Tanzania, we partnered with NYP+ to increase the demand and uptake of HIVST among students in higher learning institutions (HLIs) in Dar es Salaam, Morogoro, Dodoma, Arusha, and Iringa. Despite the availability of HIVST kits, awareness and usage remained low. Through a youth-friendly, creative media approach and the #Jipime social media campaign, we reached 4.5 million people from May to August 2024, engaging 29% men and 71% women, with 490 direct interactions. University Health Centers reported a significant rise in students seeking HIVST services, improving early detection and linkage to care. We urge young people to take charge of their health. #Jipime and know your status today!